Krka has launched Cladaxxa, a broad-spectrum antibiotic for the treatment of respiratory, digestive, urinary, skin and dental infections in dogs and cats.

Cladaxxa is a combined amoxicillin/clavulanic antibiotic, which Krka says is bioequivalent to the market reference product1,2,3,4.

The new product is available in three strengths of flavoured tablet, with the 200/50 mg formulation also licensed for cats. 

Cladaxxa is presented in blister packaging to protect the clavulanic acid, which is highly sensitive to moisture.

The tablets are ready-scored to help with accurate dosing and halved tablets can be returned to the protective blister packaging to be used within the following 24 hours. 

Cladaxxa comes in packs of 60 or 100 tablets.

Krka’s National Sales Manager Will Ridgway, said: "Treating bacterial infections is an important everyday task for vets in practice.

"Cladaxxa is a great example of Krka using its expertise in end to end product design to deliver efficacy and value to our customers.”


  1. Comparative, single-dose, 2-way cross-over bioavailability study of two Amoxicillin/Clavulanic acid 200 mg/50 mg tablet formulations in dogs under fasting condition. Krka study code: 18-V/50. Krka, d.d., Novo mesto; Šmarješka cesta 6, 8501 Novo mesto, Slovenia. / Comparative, single-dose, 2-way cross-over bioavailability study on two amoxicillin/clavulanic acid (40 mg/10 mg tablets) formulations in fasting in cats. Krka study code: 19-V/56. Krka, d.d., Novo mesto; Šmarješka cesta 6, 8501 Novo mesto, Slovenia.
  2. J. E.maddison, A.David, J.Watson, J. Elliott: Small Animal Clinical Pharmacology (Second Edition), 2008, Chapter 8 - Antibacterial drugs, Pages 148-85.
  3. Gomez-Poveda B and Moreno MA (2018) Antimicrobial Prescriptions for Dogs in the Capital of Spain. Front. Vet. Sci. 5:309. doi: 10.3389/fvets.2018.00309.
  4. The United States Pharmacopeial Convention. Amoxicillin and Clavulanate (Veterinary-Systemic). Contin Educ Pract Vet 2007; 1-4.

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