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VetNurse.co.uk has been asked to publish the following announcement from The University of Liverpool
Hydrocortisone aceponate (Cortavance®, Virbac Animal Health, Bury St. Edmunds) is a potent but very safe topical glucocorticoid. A recent publication1 clearly demonstrates both its safety and efficacy. In this trial clinical lesions scores were decreased by more than 50% in 11 of 15 dogs after 28 days, and no changes to haematology, biochemistry and ACTH stimulation tests were seen in dogs treated once daily to every other day for up to 70 days.
We have, however, become aware that the wording in the notes for the nurses’ proceedings for the recent BSAVA annual congress has led some people to make the erroneous conclusion that hydrocortisone aceponate is a mild steroid. The text listed glucocorticoids in order of the potency of their adverse effects, not clinical efficacy, although this isn’t clear from the wording. The intention was to emphasise that the side-effects were very mild, not that hydrocortisone aceponate isn’t effective. We can see how this mistaken interpretation has arisen and apologise for any misunderstanding.
Ms Vanessa Schmidt, RCVS Trust/Schering Plough Resident in Veterinary DermatologyDr Neil McEwan, Senior Lecturer in Veterinary DermatologyDr Tim Nuttall, Senior Lecturer in Veterinary Dermatology
The University of Liverpool Faculty of Veterinary Science, Leahurst Campus, Chester High Road, Neston, Cheshire, CH64 7TE.
1. Nuttall TJ, Mueller RS, Bensignor E, Verde M, Noli C, Schmidt V, Rème C. Efficacy of a 0.0584% hydrocortisone aceponate spray in the management of canine atopic dermatitis: a randomised, double blind, placebo-controlled trial. Veterinary Dermatology 2009; available online 03 April 2009: DOI 10.1111/j.1365-3164.2009.00756.x
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