View all veterinary jobs
Published in Frontiers in Veterinary Science, the model is a "hybrid causal Bayesian network" designed to enhance existing tools by analysing complex relationships between risk factors1.
It combines data from electronic health records, owner questionnaires, previous studies and veterinarian expertise.
Waltham says the model confirms the importance of risk factors including breed and size, age, head shape and quality of home dental care, and quantifies the probability of a dog having periodontal disease based on the presence of these factors.
Dr Stephen Makin, Vice President Waltham Petcare Science Institute, said: "This breakthrough is more than just a scientific achievement; it's a potential game-changer for canine oral health.
"Supported by AI, we are moving from detection to prediction, empowering veterinarians and owners with the ability to provide proactive and personalised oral care.
"This could fundamentally change the health and wellbeing of our canine companions."
The new model is now being used within the Linnaeus group to flag risk for newly-registered clients.
It has also been deployed on a risk checker at: https://www.uk.pedigree.com/gum-disease-risk-checker.
In both cases, Linnaeus says the objective is to get information to pet owners earlier, particularly for breeds where risk is substantially higher, to help drive early preventive care.
However, the company says this is only a fraction of what this kind of foundational model can do, and that it is exploring a range of further applications — including how it might work in combination with other clinical tools and diagnostics to support decision-making more directly at the point of care.
Reference
In the study: "Effects of human-animal interaction on salivary and urinary oxytocin in children and dogs1", oxytocin levels were recorded in 55 children and their pet dogs.
Oxytocin is associated with positive emotions, the reduction of stress and the formation of social bonds.
Oxytocin levels were tracked in both the children’s and dogs’ urine and saliva before and after they interacted.
Researchers say this is one of the first studies to examine the benefits of human animal interactions for both humans and dogs.
For the study, the children's oxytocin levels were measured when they interacted with their own pet dog, with an unfamiliar dog (a trained therapy dog), and when they engaged in solitary play.
The study found that:
The researchers concluded that the results support the hypothesis that oxytocin pathways may shape and respond to social interactions between children and dogs, highlighting an important role for companion animals in child development.
https://www.waltham.com/oxytocin-children-and-dogs
The 8-week study1, which was part-funded by the ISAZ/Waltham Petcare Science Institute Collaborative Research Award and Canines Providing Assistance to Wounded Warriors (C-P.A.W.W.), compared the effects of walking with a shelter dog vs. walking with a human and the impact they had on psychological stress indicators, PTSD symptoms and the stress in reintegrating military veterans.
The veterans in the study who walked with shelter dogs experienced improved rate variability and decreased levels of salivary cortisol – both signs of relaxation and improved stress response.
Waltham points to a Journal of Psychiatric Research estimate that up to 25% of military veterans who have transitioned out of active duty would meet the criteria for a diagnosis of PTSD2. This, says the Institute, could mean that up to 625,000 of the 2.4 million3 military veterans currently living in the UK could potentially be living with this mental health issue.
Dr Kay O’Donnell, Ph.D., Vice President of the Waltham Petcare science institute, said: “This study further highlights the potential of dog walking to improve the lives of both veterans and shelter dogs by offering veterans a way to make a difference in the lives of shelter animals – while dogs are simultaneously helping veterans with symptoms of PTSD.
"At the Waltham Petcare Science Institute we believe we have a responsibility to take scientific exploration further when evidence to date shows us that pets can be part of addressing conditions like PTSD. It’s important we undertake rigorous studies to understand how companion animals may provide a benefit and we’re proud to be part of this study, which takes us another step forward in understanding the human-animal bond."
References
The first, carried out by Nanna Luthersson and colleagues and published online in theJournal of Equine Veterinary Science in March, evaluated the laminitis risk factors in a group of Danish horses and ponies.1 It confirmed that Cold-blooded type animals <149cm, such as certain native ponies, as well as those being kept on high quality pasture were at an increased risk of developing laminitis for the first time. It also highlighted the important role that a change in grass intake, in terms of both type and amount, may play at any time of the year not only the spring as commonly thought.
The second study, funded in part by the PetPlan Charitable Trust, British Veterinary Association Animal Welfare Foundation Norman Hayward Fund and the Laminitis Trust, was undertaken in conjunction with Nicola Menzies-Gow (Royal Veterinary College) and published online in the Equine Veterinary Journal (EVJ) in August. The study evaluated the risk factors for the development of laminitis prior to the occurrence of the disease.2 It identified that low concentrations of the adipose tissue derived hormone adiponectin, together with high serum insulin concentrations (at rest and as part of a diagnostic test for PPID) may predict an increased risk of future pasture-associated laminitis.
It is hoped that future studies will be able to generate more robust cut off values, which will more accurately predict future laminitis development in an individual animal.
The RVC in collaboration with Waltham is now taking this forward through a study in which these markers are measured regularly, in conjunction with a detailed management assessment, in a group of ponies with no known history of laminitis at the start.
Clare Barfoot RNutr and the research and development manager at Spillers said: "The Danish study gives us important practical facts about the susceptibility of cold-blooded types, and is particularly applicable to natives in the UK. The second study gives hope that there may soon be a test or series of tests that will help predict those at an increased risk of suffering from pasture associated laminitis in the future thereby reducing the number of animals affected by this debilitating condition. In the meantime until we fully understand the condition it is sensible to manage all the risk factors we currently know about, in particular keeping your horse at a healthy weight."
The Waltham Equine Studies Group has published new research which highlights the effectiveness of grazing muzzles as a tool to help with weight management in ponies.
The research, which was conducted in collaboration with Dr Annette Longland of Equine and Livestock Nutrition Services (ELNS) in Wales2, also showed that longer grass can be more difficult for muzzled ponies to graze, and can cause frustration-related behaviour in some individuals.
According to Waltham, grazing muzzles have already been shown to reduce the pasture intake of ponies by around 80% by significantly reducing bite size and intake.1 Ponies fitted with grazing muzzles may spend more time engaging in foraging and eating than their non-muzzled counterparts, yet the majority either lose weight or retain their body condition. This in turn helps reduce susceptibility to obesity and related disorders, such as insulin dysregulation and laminitis.
Four mature ponies were selected for the study. Their dry matter (DM) and water-soluble carbohydrate (WSC) intakes were measured in spring, summer, and autumn pastures on four, three-hour occasions per pony per season when fitted with or without a grazing muzzle. In addition ponies, with and without muzzles, were allowed to take 10 bites of swards maintained at different heights.
When wearing grazing muzzles pasture intake was reduced by 77% during spring and summer and by 83% during the autumn. Without muzzles the ponies generally reduced the sward length by half with the first bite but when muzzled the reduction was variable and the ponies appeared to experience greater difficulty in accessing the longer versus the shorter swards.
The short (less than 10cm), upright, grass appeared to be the easiest to eat, as leaf blades and stems protruded through the holes in the muzzle. The medium and long swards proved more difficult. They bent under the pressure of the muzzle and became flattened, causing the ponies to adopt various strategies to access the grass. In some cases they pawed the ground to unearth the sward and access it through the muzzle. Alternatively they rammed the solid base of the muzzle hard onto the grass, causing it to buckle and make some blades or stems accessible. These were then yanked vigorously often causing the entire plant to be uprooted and eaten.
Water soluble carbohydrate levels in the sward were similar across the seasons although they were slightly higher in autumn. However, once muzzled the ponies’ intake of WSC wasn’t significantly different across the seasons; strengthening the evidence that the use of grazing muzzles is effective.
Clare Barfoot RNutr and the research and development manager at Spillers said: "While the frustration displayed when the muzzled ponies were on longer grass swards indicates that care should be taken to provide an accessible grass length, grazing muzzles remain an effective weight management tool. They allow turnout over large areas, increasing exercise and allow slow “trickle” feeding, to control weight gain and reduce the risk of obesity-related disorders, without significantly compromising the natural behaviour and wellbeing."
Waltham says grazing muzzles must be used with care, should be properly fitted and horses and ponies should be adapted gradually to wearing them. Group and individual behaviour should be monitored closely to observe any potential concerns caused by changes to the herd dynamics. Ensure that muzzled ponies are confident in drinking and eating through their muzzles before turning them out for prolonged periods. Muzzles must not be used continuously (not more than 10 hours per day) and total exclusion muzzles are not advised. Regular weight monitoring is recommended as some individuals can still gain weight when muzzled.
Researchers from the Waltham Centre for Pet Nutrition have published two studies which reveal, for the first time, the most common bacterial species associated with gum disease in cats.
Working with veterinary dentists and the Harvard affiliated Forsyth Institute, researchers used DNA sequencing technologies to identify 267 bacterial species present in feline dental plaque and build a database detailing the differences between bacterial populations in healthy cats and those in cats with gum disease.
Dr. Ian Davis, Oral Health Researcher at WALTHAM, part of Mars Petcare, said: "This knowledge is a first step in understanding the potential for improving oral health of cats through dietary interventions that target disease-associated bacteria."
The studies also revealed that the bacterial species in feline plaque were more similar to those observed in canine plaque than to those found in humans. This suggests that interventions targeted at bacteria which cause oral disease in humans are unlikely to be effective in cats, and there is more potential to learn from interventions that work well in dogs.
Dr. Davis added: "It’s important for pet owners to know that cats are just as susceptible to gum disease as dogs and understand the importance of maintaining a good oral hygiene routine; ideally including tooth brushing and dental treats or a specific dental diet".
The first study was published in Veterinary Microbiology in February 2015. The second was published on 25th November in PLOS ONE, and can be downloaded here: http://dx.plos.org/10.1371/journal.pone.0136986.
The Waltham Equine Studies Group has announced the results of two pieces of research designed to improve understanding of the best nutritional support for older horses, whether they are healthy or diagnosed with Pituitary Pars Intermedia Dysfunction (PPID or Cushing's).
The first study: A comparison of nutrient digestibility between adult and aged horses, conducted by the Department of Large Animal clinical Sciences and Animal Science, Michigan State University and The Waltham Equine Studies Group, confirmed (in contrast to earlier work) that there was no difference in digestibility between healthy adult and aged horses when fed a variety of common equine diets.1
In the second study: Characterisation of the faecal bacterial community in adult and elderly horses fed a high fibre high oil or high starch diet, the Institute of Biological Environmental and Rural Sciences, Aberystwyth University, The Waltham Equine Studies Group and Michigan State University used the same horses as the previous study but this time looked at their gut microflora. The results showed that although no significant differences in individual species of bacteria were found, ageing was, however, associated with a reduction in bacterial diversity. This, say the authors, may in part explain why older animals can be at increased risk of intestinal disturbances.2
An abstract that summarised part of the Waltham Equine Studies Group's work on the effect of additional supplementation on aged horses with and without PPID was presented at the 2nd Dorothy Havermeyer Geriatric Workshop in the USA last November.3 This work, carried out in conjunction with Dr Amanda Adams at the University of Kentucky showed that age is key in influencing inflammation and metabolism rather than whether the horse is PPID positive or not.
Professor Pat Harris, head of the Waltham Equine Studies Group, said: "For the parameters we monitored, the research showed that it is being old that is the issue, rather than having PPID."
Clare Barfoot RNutr and the research and development manager at Spillers said: “This should give us a better understanding of the effects of diet and age on metabolism in order to determine optimal nutrition for the senior horse. Preliminary work suggests that this new research may change the way we think of feeding the older horse. Waltham’s work continues to ensure that Spillers feeds remain at the forefront of equine nutrition, for the better health of horses everywhere.”
The Waltham Centre for Pet Nutrition has announced new research - published in BMC Vet Research1 - which examined the progression of periodontal disease in miniature schnauzers and found that without effective and frequent oral care, dental disease developed rapidly and advanced even more quickly with age.
Over the course of 60 weeks, full mouth examinations were conducted on 52 miniature schnauzers ranging in age between 1.3 and 6.9 years. Prior to the study, each dog had a regular oral care routine that included tooth brushing. This was suspended a week before the initial dental assessment. Of the 2,155 teeth examined, all entered the study with some level of gingivitis, while only 23 teeth entered with periodontitis.
Every 6 weeks, levels of gingivitis and periodontitis were assessed around the whole surface of each individual tooth by measuring periodontal probing depth, gingival recession and furcation exposure. Teeth were assessed for the level of gingivitis (scored between 0 and 4) and periodontitis (PD1 - up to 25% attachment loss and PD2 - between 25 to 50% attachment loss). Teeth from only one dog in the study did not progress to periodontitis.
Researchers found that, without regular oral care, the majority of dogs developed the early stages of periodontal disease within six months and dogs above the age of four developed periodontal disease even faster. The degree to which periodontal disease progressed varied based on the type of tooth and location on the tooth.
Furthermore, the study showed that periodontitis developed regardless of the visible signs of gingivitis, which had previously been believed to reliably precede it. Therefore while a visual inspection may be sufficient to detect a disease like gingivitis, it is not useful in detecting the onset of periodontitis and may not reveal the areas at greatest risk for dental disease.
Dr Stephen Harris, leader of the oral care team at WALTHAM, part of Mars Petcare said: "We all want to do the very best for our pets' health, and the study showed us that there's more than meets the eye when it comes to small dogs' oral health.
"Some pet owners "lift-the-lip" and look at a dog's gums to get a sense of its oral health, but this research shows they could be missing important early signs of dental disease. The findings should encourage all dog owners to establish an oral care routine that consists of regular tooth brushing supplemented with dental chews and veterinary checks. It's important for all dogs, but we know that small dogs like miniature schnauzers are at an even higher risk of developing severe dental problems."
Reference:
A collaborative team of researchers from the Waltham Centre for Pet Nutrition has shown that adding moisture to a cat's diet leads to an increase in activity and may help slow down weight gain.
In a series of studies conducted in partnership with the University of Aberdeen, Waltham scientists found that cats fed a dry diet with added water were more physically active and gained less weight than those cats fed the dry diet alone. According to the Centre, this is the first time reduced energy density diets have been associated with an increase in physical activity levels in cats.
Waltham scientist and author of the study, Dr. Penelope Morris, said: "These findings advance our understanding of the factors that influence body weight in cats and provide a strong basis for further research.
"Obesity is a growing problem in the cat population, recent figures indicate that up to 50 per cent of cats are either overweight or obese. These findings could have important implications for developing tailored diets that meet cats' energy and nutritional needs."
The research is part of a wider programme of ongoing collaborative research into the effect of food and nutrition on body weight in both cats and dogs.
The research has been published in the June edition (Volume 95, Issue 3) of the Journal of Animal Physiology and Animal Nutrition and is available in print and online: http://onlinelibrary.wiley.com/doi/10.1111/j.1439-0396.2010.01107.x/abstract