Test and Treat, a company which develops point of care tests for the detection of urinary tract infections, has launched U-Treat, a urine test which it says could change the way veterinary surgeons approach cases of suspected urinary infections in dogs and cats.

The patient-side test identifies urinary tract infection (UTI) and the best antibiotics to treat the condition, with the results produced in minutes.

Test and Treat says the new test means that vets will no longer have to treat empirically while a urine sample is sent to an external laboratory. Nor will you have to risk delaying treatment until the results are received. 

In addition, the company says that the test will help support the responsible use of antibiotics, which is particularly important given that Enterococci strains identified in canine urinary infections have been found to be resistant to three or more antimicrobials1.

U-treat is a two-part test. The first part of the test detects the presence of a urinary infection. The second part of the test looks at antibiotic susceptibility, showing the best choice of antibiotic and identifying those that won't work due to antimicrobial resistance. 

Using the principles of bioluminescence, U-Treat removes host cell ATP before lysing bacterial cell walls to release bacterial ATP, which is then detected using a luminometer. The initial detection of infection test takes five minutes and the susceptibility test takes 30 minutes.

Clinical evaluation of the test in cats and dogs was carried out at University of Tennessee in conjunction with Prof. David Bemis of Cornell University. The company says U-Treat demonstrated high levels of sensitivity (97.1%) and specificity (92%), compared to lab tests. 

The test is currently validated for use in dogs and cats and is being investigated for use in horses. While the test will launch first in the veterinary world, it also has scope to cross over into human medicine where there is potential to use it in general practice, paediatric and geriatric care.

Ron Turner, CEO and Scientific Director of Test and Treat said: "We've already sent our first orders to the US and have being talking at veterinary conferences about the technology - so we know vets are keen to get access to this new diagnostic test. Fast, reliable and accurate results mean that it's easier to put together a rational treatment plan that they can be very confident will work because they have the evidence."

Test and Treat is based near Newmarket in Suffolk and orders for the test are now being taken from veterinary practices in the UK. Full training will be given and the desk-top equipment (incubator, luminometer and reader) required to run the test can be supplied.

The company, which has attracted government enterprise funding, is also interested in hearing from veterinary surgeons who might be interested in investing in the technology and helping to expand its use.

To place an order, contact James Turner, General Manager on 01638 501974, email: jamest@tandtreat.com or visit http://www.tandtreat.com.

Reference

  1. https://www.msdvetmanual.com/pharmacology/systemic-pharmacotherapeutics-of-the-urinary-system/bacterial-urinary-tract-infections

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