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The Animal Health Trust has announced a research project which aims to improve the way dogs are treated for cancer. As part of the project, the charity is appealing to veterinary practices to send samples taken from dogs diagnosed with cancer.
Using the samples, the AHT's Oncology Research Group aims to develop prognostic tests for a number of canine cancers. These tests will assist veterinary professionals in predicting how individual tumours will behave and respond to treatment. It means that each dog will be offered the best treatment for its individual case, ensuring that dogs which do not require aggressive therapy are spared the rigours and possible side effects associated with such a treatment.
The samples required are surplus small pieces of the biopsies of suspected tumours, collected for diagnostic histopathology. Cheek swabs, or blood samples that are surplus to those that are often collected for standard clinical investigations are also required. Samples will be submitted for research only with the written consent of each dog owner.
Mike Starkey, from the AHT's Oncology Research Group, said: "To make progress we need to collect many samples of many different tumours. We simply need vets to send us freshly frozen (not fixed in formalin) biopsies of suspected tumours."
Samples of the following tumour types are needed from the following breeds:
Sue Murphy, the AHT's Head of Oncology, said: "We know cancer is a major cause of death in dogs. The research we are doing here will arm us all with the ability to make better informed decisions about the right course of treatment for each patient."
The samples will also aid with the AHT's research into inherited genetic defects. Researchers are investigating to find out why certain pedigree dogs have an increased risk of developing a specific cancer. The AHT is part of a European research group working on the 'LUPA project' which aims to develop DNA tests to identify dogs which carry the mutations. This should enable breeders to alter their breeding strategies to reduce the incidence of dogs affected by those cancers. It will also allow vets to carefully monitor dogs who have an increased risk of developing cancer.
Mike Starkey added: "The help from veterinary practices and dog owners is invaluable in this research. Without the samples we're unable to progress our work."
If you would like further information about the project, please contact Mike Starkey on 01638 555603 or email mike.starkey@aht.org.uk
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