vn12.2 ku questions

Re: vn12.2 ku questions

Saskia Quinn — Fri, 24 Apr 2009 23:15:40 GMT

Absorption - Firstly, the drug must be given in a suitable form at an appropriate site of administration. If local action is required, absorption from the site is a disadvantage, but when systemic effects are needed, absorption is essential. Unless given by the iv route, drugs need to penetrate cell membranes that form a barrier between the drug and the circulation.

Interaction - A drug interaction occurs when the effects of one drug are altered by the effects of another. Occasionally, these interactions are beneficial, e.g when using diuretics and angiostensin-converting enzyme (ACE) inhibitors in the treatment of hypertension, but most of the time we regard them as a problem.

When pharmaceutical preparations are mixed for administration by virtually any route, interactions may occur between the active ingredients or the adjuncts in the formulations. Incompatibilites may result in precipitation, chemical inactivation and a change in colour, taste or the physical form of the preparations.

Re: vn12.2 ku questions

gemma — Fri, 24 Apr 2009 22:04:06 GMT

thank you very much!:)

Re: vn12.2 ku questions

Claire Cameron — Fri, 24 Apr 2009 21:47:36 GMT

this is along the lines of what i put....

half life - the rate in which is takes the body to reduce the levels of substance in the body to half its original amount

side effect - an unwanted known effect caused by a drug (ie gastrointestinal upset following NSAIDs)

reaction - an unknown effect caused by a drug

interaction - the situation where a drug is drug is affected by another substance given

therapeutic index - the comparison between the therapeutic effect and toxic effect, ie a drug with a narrow therapeutic range means there is a small margin between "safe" and "toxic" dosages