pharmacology query :/

Re: pharmacology query :/

Delightful — Sat, 03 Dec 2011 15:48:25 GMT

You could try here im sure you will find the information you are looking for

www.vetformulary.com

Re: pharmacology query :/

Julie-Anne Wilson — Sat, 03 Dec 2011 15:36:33 GMT

I've seen the extremities rigidity and paddling happening after Propofol induction. I can't say what causes it though, just know that if it happens and doesn't stop after a minute or so, we give Diazepam IV

Re: pharmacology query :/

Nick Shackleton — Sat, 03 Dec 2011 14:33:05 GMT

you can always reference the data sheet or BSAVA Formulary

Re: pharmacology query :/

Katy — Sat, 03 Dec 2011 14:02:54 GMT

If you look on the electronic medicine compendium (for humans - lol) www.medicines.org.uk

type in propofol in the search box and it should bring up the SPC (specific product characteristics) in there it has pharmacology info and sometimes mechanism of action e.g. how a drug works on the body.

That might help?

Re: pharmacology query :/

fnewboult — Thu, 01 Dec 2011 18:11:04 GMT

I'd say have a look through some journals online (your college should have some kind of access to them)... I think there's one called "veterinary anaesthesia and analgesia" which surely ought to have something in there somewhere.

Re: pharmacology query :/

Nicola Smith — Thu, 01 Dec 2011 08:19:32 GMT

Even though it only ststaes a small number of animals the noah compendium is s good thing to reference, or maybe contact the drug companies who make it who may be able to point you in right direction of some articles?

Re: pharmacology query :/

hissycat — Thu, 01 Dec 2011 01:12:02 GMT

To be honest I havn't witnessed it even in animals that havn't had a premed, but then in most instances a premed would be given, maybe this is why it is reported as infrequent. Could you put it down as being your own experience? Be interesting to hear what others experiences have been aswell. Good luck with the journal search, I know how frustrating it can be when you're looking for something obscure!

Re: pharmacology query :/

xhappysvn21x — Thu, 01 Dec 2011 00:13:58 GMT

thanks Hcat i seen that one but it didnt sound too believable if you know what i mean. in a "small" number of animals. seems abit brief. i seem to see it in "most" animals that have not had a premed before hand. But hey no mention of that there either. i might have a veterinary journal day tomorrow looking through articles tomorrow, although i cant think i have read any, worth a try tho. thanks

Re: pharmacology query :/

hissycat — Thu, 01 Dec 2011 00:01:52 GMT

http://www.noahcompendium.co.uk/abbott_laboratories_ltd/propoflo_10_mg_ml_emulsion_for_injection_for_dogs_and_cats/-22948.html

Mentions excitation in a small number of animals. Hope this helps a bit, one reference at least. As to why it happens a good anaesthesia/pharmacology book/journal article may help, maybe fit in a very brief explanation. Good luck:)