Urinary incontinence - Urilin/Propalin vs Incurin

Re: Urinary incontinence - Urilin/Propalin vs Incurin

Andrew Groom — Wed, 07 Jul 2010 11:47:24 GMT

Yes same active

Re: Urinary incontinence - Urilin/Propalin vs Incurin

melloyello — Wed, 07 Jul 2010 08:41:53 GMT

Propalin: stimulates the alpha 1 adrenergic receptors (causing an increase in and stabilisation of the closure pressure of the urethral sphincter)

Incurin: treats hormone responsive incontinence in spayed bitches by sensitising the urethral smooth muscles to alpha 1 adrenergic stimulation. (Because this is hormone based dogs can sometimes look like they are in season to other dogs).

There is also a newer drug called Enurace, that has a dual claim. Like Propalin it works on the alpha 1 receptors of the sphincter but it also works on the alpha 2 receptors in the bladder wall.

Enurace and Propalin can be used for all causes of incontinence, Incurin works only on incontinence caused by hormone deficiency. You can use Enurace and Incurin together if needed.

Cheers!

Re: Urinary incontinence - Urilin/Propalin vs Incurin

Caro Laithwaite VN — Tue, 06 Jul 2010 23:27:04 GMT

Choice is incurin and proplain

Re: Urinary incontinence - Urilin/Propalin vs Incurin

Sal the 1st — Tue, 06 Jul 2010 21:47:09 GMT

isnt urilin and propalin the same drug? what you get with one you will get with the other?

Re: Urinary incontinence - Urilin/Propalin vs Incurin

Caro Laithwaite VN — Tue, 06 Jul 2010 21:23:52 GMT

Santa was as soft as a soap bubble and never changed on any of the meds but not sure if that is a help or not.

Re: Urinary incontinence - Urilin/Propalin vs Incurin

Honeybadger — Tue, 06 Jul 2010 21:01:52 GMT

Thanks for your answers. The reason I ask is that Jess (my 8yo neutered dalmatian) occasionally has accidents when she is asleep or very relaxed. It usually happens for 2 days in a row every couple of months. At the moment it is no big deal but over time it seems to becoming more often. She is a resuce and can be slightly fear aggressive towards certain people so I was worried about using Propalin as I know it can adversely affect their behaviour. I guess when the time comes I could try with Urilin and see how it goes.

Re: Urinary incontinence - Urilin/Propalin vs Incurin

Caro Laithwaite VN — Fri, 02 Jul 2010 06:20:56 GMT

I have used both on Santa when she was alive. Strangely l found that after a time she would become tolerant to one and l would swop to the other. When that became tolerant swop back weird and don't know any others this happened to but it happened with Santa.

Re: Urinary incontinence - Urilin/Propalin vs Incurin

Steph Phillips — Thu, 01 Jul 2010 21:52:04 GMT

we stock both.. but have more clients on incurin.. dunno why! I'm going to ask tomorrow now! lol

Re: Urinary incontinence - Urilin/Propalin vs Incurin

Phrin Vernon RVN — Thu, 01 Jul 2010 21:46:13 GMT

We tend to have more on propalin - not sure if this is down to owner or vet preference though!

Re: Urinary incontinence - Urilin/Propalin vs Incurin

Nicola Smith — Thu, 01 Jul 2010 21:27:56 GMT

We use more incurin as once daily dosing and does do the job, we do however have 1 dog on both that we inherited from another practice as neiter works alone - not sure whether this is strictly 'ok', but its the only option for this dog.

Re: Urinary incontinence - Urilin/Propalin vs Incurin

Sal the 1st — Thu, 01 Jul 2010 19:02:25 GMT

many owners prefer incurin because they feel it is easier to dose from my experience