Augmentin reactions

RE: Augmentin reactions

Stuart Ford-Fennah — Sat, 05 Sep 2015 14:11:18 GMT

Hi,

We have seen similar reactions as reported here but more so with the generic co-amxyclav formulations apposed to the auguentin brand

Stu

RE: Augmentin reactions

Michelle Rewcastle — Wed, 02 Sep 2015 18:42:59 GMT

We have had a lot of reactions, hives, facial oedema and erythema. We have done iv Phenegran and it seemed to have helped with the side effects fairly quick, also stopping things getting worse.

RE: Augmentin reactions

Steph Worsley — Wed, 02 Sep 2015 17:34:25 GMT

Yep we have a protocol in place now. It seems to have started following the last OOS situation...we have had probs in the past with other generic co-amoxy-clav IV preps so stopped using them full stop.

Since the last OOS situation with Augmentin we have started dispensing chlorphenamine to the patient for the first dose but only using if required. Generalised oedema has been the main sign, we have got 1 springer though who had a couple of days of IV augmentin with us and THEN had a reaction, switched him to oral synulox but still had facial swelling, stopped all amoxy and the swelling went down.....it's now written all over his paper file AND computer records not to give beta-lactams to him now :)

RE: Augmentin reactions

hobbits — Wed, 02 Sep 2015 15:18:27 GMT

Yes it's been well known around the south that there is an increase in augmentin reactions Report to the VMD. The manufacturers are aware apparently but say there has been no change in formulation and no increase in human reactions reported.

RE: Augmentin reactions

elaine elder — Wed, 02 Sep 2015 14:35:45 GMT

When augmentin was out of stock we used zinacef and we had two occasions where the patients had some facial seeking. Presumably a allergic reaction, given antihistamine and returned to normal in a few hours. Never seen it with augmentin but don't suppose it would be impossible.

RE: Augmentin reactions

Mark Hedberg — Wed, 02 Sep 2015 09:12:05 GMT

What's your IV aftercare like? I'd check that out first, as having occasional yet not universal drug reactions is fairly unlikely if not a bad batch.