Propofol Infusions

Re: Propofol Infusions

Feezy — Thu, 08 May 2014 15:56:04 GMT

You all are very wise! Thanks again, will print all this out...

Re: Propofol Infusions

Angiy Michael — Mon, 05 May 2014 03:35:06 GMT

I agree with Susanna..try not be scared..you know already what you need to be monitoring as you do this in anaesthesia all the time so fromt hat perspective you are well equipped at the start point .

A syringe driver is an extremely useful piece of kit to have if possible if you find you are going to be doing them regularly . Failing that infusions can be made in small IV bags to administer via a volumetric drip pump which gives a slightly more controlled delivery method than doing manually .

One thing I would point out is not all Propofol is the same and some is not suitable for use for continuous infusions due to the preservative used ..so chekc your manufacturers leaflet beforehand to make sure it can be used in this way .

The emergency hospital I worked at did them on an extremely frequent basis and we eventually invested in several syringe drivers for the purpose . We stocked two different makes of propofol for this reason ..I'm afraid I can't recall the manufacturers.

We used it quite frequently for uncontrolled seizures that didn't respond to normal treatments and in particular found it especially useful for severe pyremethrin toxicity in cats that were having uncontrolled seizure activity .

We also used a similar method for pain bags for severe trauma cases where we delivered a controlled continous dose of analgesics and sedative agents to allow a period of recovery .

Re: Propofol Infusions

Feezy — Thu, 01 May 2014 12:27:22 GMT

Thanks Susanna! Will print out your email and keep it for future reference! Brilliant!

And thanks Katie too, I noticed that! Isn't it weird, as soon as you start considering something it comes up in the mags! Its a great article too!

Re: Propofol Infusions

Katie Charley — Wed, 30 Apr 2014 18:35:07 GMT

Hi.

I just read an article today about constant rate infusions including total intravenous anesthesia. It is in the latest issue of 'The Veterinary Nurse' magazine. Sorry i don't have it with me to give issue numbers etc.

Re: Propofol Infusions

Susanna Taylor — Tue, 29 Apr 2014 21:44:32 GMT

Propofol TIVA works fine and is not as scary as it first sounds! You can just give little increments IV every 5-10mins, monitoring for signs of lightening, but the downside of this is that it can give quite a zig-zagy GA and it quite time consuming. The ideal thing to do is to give it by a syringe driver as a CRI. Doses of 0.1-0.4mg/kg/min are normally needed (0.6-2.4ml/kg/hr). I normally start at 0.2mg/kg/min for healthy animal and titrate up as required.

Monitoring is exactly the same. At higher doses respiratory depression is common and IPPV may be required.

Recovery is pretty similar to iso really. If they have a good premed, excitement is rare in my expereience

Propfol TIVAs are generally required for bronchoscopy or airway surgeries. What are you needing it for?

Here is a good reference http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3573635/

Hope helps, feel free to ask if you have any other Qs

Re: Propofol Infusions

Feezy — Thu, 24 Apr 2014 11:13:50 GMT

Propofol infusions in dogs by the way for above post!