MLK CRI calculations

Re: MLK CRI calculations

Rhiannon Hutton — Fri, 19 Jul 2013 22:55:57 GMT

Thanks guys!

Re: MLK CRI calculations

Susanna Taylor — Thu, 18 Jul 2013 22:23:12 GMT

I have used both morphine and methadone in MLKs, there is less evidence about methadone, but it is used. Some people refer to it as a MeLK to show the difference.

Only downside to above recipe is that it can be used post op without overdosing fluids or under-dosing analgesia. I would recommend making a 250ml bag up to run at 2ml/kg/hr and then using a second CSL infusion to top up to surgical fluid rates during the procedure.

Doses I have used at the RVC are

meth/morp 0.1mg/kg/hr
Ketamine 0.6mg/kg/hr
Lidocaine 3mg/kg/hr

You can also leave out the lidocaine and use the same dose of MK for cats

Re: MLK CRI calculations

Catherine Raymond — Mon, 15 Jul 2013 21:33:05 GMT

Have copied from the chart we use for orthopaedics:

Comfortan 0.6ml / Lidocaine 3.75ml / Ketamine 0.3ml mixed with 495mls Ringers. Infused at 10ml/kg/hr.

Equivalent to

Methadone 0.12mg/kg/hr
Lidocaine 1.5mg/kg/hr
Ketamine 0.6mg/kg/hr

Re: MLK CRI calculations

ga777 — Sat, 13 Jul 2013 11:07:33 GMT

To my knowledge, methadone is not widely used in MLK drips, it is morphine, lidocaine and ketamine. The reason for this is that there is not enough published data on the cumulative effects of methadone. So although Methdone is the licensed mu agonist, morphine can be used in this combination under the cascade. We use the MLK drips in all our orthopaedic ops and find it is very effective.

MLK CRI calculations

Re: MLK CRI calculations

Re: MLK CRI calculations

meth/morp 0.1mg/kg/hrKetamine 0.6mg/kg/hrLidocaine 3mg/kg/hr

Re: MLK CRI calculations

Re: MLK CRI calculations

meth/morp 0.1mg/kg/hr
Ketamine 0.6mg/kg/hr
Lidocaine 3mg/kg/hr