https://www.vetnurse.co.uk/f/clinical-discussions/16760/dexdomitor Hi, just wondering anyone using this and how do you find it compared with normal. We use for premed for cat neuters with vetergesic - in ery small doses - I know the new one you are meant to need less but it is more dilute - is it easy to measure smallen-USTelligent Community 10https://www.vetnurse.co.uk/thread/127570?ContentTypeID=1Mon, 20 Feb 2012 12:19:25 GMT1a0763ec-3885-442c-853e-6cef656dfec5:d2374ff5-02a0-46c1-a753-6f33a7d94a44Mark Hedberg<p>Dom and torb make a gorgeous premed, I feel. just the thing for a fractious cat castrate. :)</p><div style="clear:both;"></div>https://www.vetnurse.co.uk/thread/127569?ContentTypeID=1Mon, 20 Feb 2012 12:18:03 GMT1a0763ec-3885-442c-853e-6cef656dfec5:5de06a23-f5fc-4375-92b6-b4d108bc88c1emvn80<p>Hi, the volume you use of dexdomitor works out the same volume that you would have used for Domitor.... You need half the dose but it is half the concentration (0.5mg/mL instead of Domior which is 1mg/mL) so if you previously used 10mcg/kg of Domitor to premed a cat with you would use 5mcg/kg of Dexdomitor, but the volume works out the same- for a 4kg cat it would be 0.04mLs of both. With Dexdomitor you should only need to use half the dose compared to Domitor because it contains only the active isomer of medetomidine. Domitor contains 50% of the active isomer and 50% of the inactive isomer. It is exactly the same drug (just without the inactive isomer) so recover, sedation etc should be identical, as are the side effects, saying that some people subjectively think it doesn&#39;t give quite as reliable sedation at the half dose... Hope this helps</p><div style="clear:both;"></div>